Production and use of Diels Alder adducts of vinyl porphyrins and of compositions containing such adducts

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dc.contributorThe University of Toledo; Medical College of Ohio
dc.contributorMorgan, Alan R.
dc.contributorSelman, Steven H.
dc.date1994-10-11
dc.date.accessioned2024-05-24T16:50:29Z
dc.date.available2024-05-24T16:50:29Z
dc.descriptionFamilies of Diels Alder adducts and of metal complexes of Diels Alder adducts, which are useful as particularly active compounds for use in photodynamic therapy, are disclosed. The Diels Alder adducts and a preferred family of metal complexes have the structures of Formula 1, Formula 2, Formula 3 and Formula 4, below: ##STR1## where R1, R2, R3 and R4 can be the same or different, and each is methyl or ethyl, R5, R6 and R7 are ethyl, R8 is an alkyl group other than t-butyl having from one to four carbon atoms and M comprises a metal cation, e.g., Sn or Zn, that is complexed with two of the nitrogens of the adduct. The use of the adducts and complexes in photodynamic therapy is also disclosed.
dc.formatapplication/pdf
dc.identifierutoledo:1272
dc.identifieriid:utpatents-US5354858
dc.identifierPatent No.: US5354858
dc.identifierAppl. No.: 07/912079
dc.identifier.urihttps://hdl.handle.net/20.500.14324/6004
dc.language.isoeng
dc.publisherUnited States Patent and Trademark Office
dc.rightsNo Copyright - United States
dc.subject540/145
dc.titleProduction and use of Diels Alder adducts of vinyl porphyrins and of compositions containing such adducts
dc.typeText
dc.typepatent

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