Materials and methods useful to induce vacuolization, cell death, or a combination thereof

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dc.contributorThe University of Toledo
dc.contributorMaltese, William A.
dc.contributorErhardt, Paul W.
dc.contributorOvermeyer, Jean H.
dc.contributorTrabbic, Christopher
dc.date2015-06-23
dc.date.accessioned2024-05-26T02:15:04Z
dc.date.available2024-05-26T02:15:04Z
dc.descriptionThe present invention provides materials and methods to induce cell death by methuosis, a non-apoptotic cell death mechanism, to induce vacuolization without cell death, or to induce cell death without vacuolization. Small molecules herein are useful for treating cell proliferation disorders or anomalies, particularly, but not exclusively, cancer. Methods related to the research and pharmaceutical use of the small molecules are also provided herein.
dc.formatapplication/pdf
dc.identifierutoledo:1456
dc.identifieriid:utpatents-US9061994
dc.identifierPatent No.: US9061994
dc.identifierAppl. No.: 14/616390
dc.identifier.urihttps://hdl.handle.net/20.500.14324/6944
dc.language.isoeng
dc.publisherUnited States Patent and Trademark Office
dc.rightsNo Copyright - United States
dc.subjectC07D 209112
dc.titleMaterials and methods useful to induce vacuolization, cell death, or a combination thereof
dc.typeText
dc.typepatent

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