Iron(III) complexes as contrast agents for image enhancement in magnetic resonance imaging

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United States Patent and Trademark Office

Abstract

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A compound of formula (I): ##STR1## wherein, R1 is independently selected from methyl and ethyl and R2 is independently selected from hydrogen, alkyl, and substituted alkyl. The compound is capable of functioning as a ligand and complexing with paramagnetic Fe(III) ion for use as a second-sphere contrast enhancing agent for magnetic resonance imaging of tissue. The present invention also relates to a method of administering the second sphere contrast agent.

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424/9.361

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https://hdl.handle.net/20.500.14324/6370

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University of Toledo U.S. Patents