Use of formin agonists in overcoming brain tumor radio- and chemo-resistance by targeting tumor microtubes

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United States Patent and Trademark Office

Abstract

Description

Compositions and methods for inhibiting brain tumor proliferation, or for inhibiting or halting TM formation, invasion, and/or proliferation, or for rendering brain tumor cells sensitive to chemotherapy or radiation, or for treating a brain tumor, or for inducing cell death, involving mDia agonists such as IMM01 and IMM02, are described.

Keywords

A61K45/06, A61K31/175, A61P35/00

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https://hdl.handle.net/20.500.14324/6908

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University of Toledo U.S. Patents