Compositions useful in therapy of autophagy-related pathologies, and methods of making and using the same

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United States Patent and Trademark Office

Abstract

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Lanthionine ketimine derivatives, and methods of making and using the same, are described. Included are lanthionine ketimine phosphonate (LK-P), lanthionine ketimine ester phosphonate (LKE-P) derivatives, as well as lanthionine ketimine derivatives having a tert-enamide moiety at the 2-position (NVP-LKE).

Keywords

C07F9/6544, A61P9/10, A61P19/02, A61P25/16, A61P25/22, A61P25/24, A61P25/28, A61P29/00, C07D279/12

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https://hdl.handle.net/20.500.14324/11414

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University of Toledo U.S. Patents