Methods for standardized sequencing of nucleic acids and uses thereof

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utoledo_10912.pdf (1.44 MB)

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United States Patent and Trademark Office

Abstract

Description

Methods for controlling for non-systematic error in an amplification-based next generation sequencing (NGS) library preparation are described, which method includes using an internal amplification control (IAC) sharing identical priming sites to a native nucleic acid target template of interest in a NGS library preparation.

Keywords

C40B20/04, C12Q1/6806, C12Q1/6851, C12Q1/6869

Citation

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https://hdl.handle.net/20.500.14324/4016

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University of Toledo U.S. Patents