Method for increasing HDL cholesterol levels using heteroaromatic phenylmethanes

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Publisher

United States Patent and Trademark Office

Abstract

Description

An HDL cholesterol level inducing compound and a method of administering the compound having the structural formula I. ##STR1## wherein n is 1 or 2;R1 is a heteroaromatic substituent independently selected from a five-membered heteroaromatic ring having at least one N heteroatom, a six-membered heteroaromatic ring having at least one N heteroatom, or a fused ring system having at least one five-membered heteroaromatic ring having at least one N heteroatom;R2 is independently selected from --H or phenyl; andR3 is independently selected from --H, --CH3, --OH, phenyl, phenyl substituted with Cl, OCH3, CH3, or F, fused phenyl ring system, or six-membered heteroaromatic ring having at least one N heteroatom.

Keywords

514/277, 514/399, 514/400, 514/427, 544/333, 546/272.7, 546/343, 548/340.1, 548/346.1

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