sGCa1 inhibiting compositions
Date
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United States Patent and Trademark Office
Abstract
Description
The present invention provides materials and methods useful to treat various sGCa1-expressing cancers. Materials include peptides which interfere with sGCa1's pro-survival functions, thereby resulting in apoptosis of sGCa1-expressing cells. In addition, the present invention provides screening assays, diagnostic assays, methods to prognose, methods to treat, and kits.
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Keywords
A61K38/04, A61K31/7048, A61K38/06, A61K38/07, A61K38/08, A61K38/10, C07K5/083, C07K5/103, C07K5/107, C07K5/11, C07K7/06, C07K7/08, C12N9/88, A61K38/00