Methods for protection of stratified squamous epithelium against injury by noxious substances and novel agents for use therefor

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dc.contributorThe University of Toledo
dc.contributorHudson, Richard A.
dc.contributorTillekeratne, Liyanaaratchinge M. V.
dc.contributorTobey, Nelia A.
dc.contributorOrlando, Roy C.
dc.date2004-06-01
dc.date.accessioned2024-05-25T19:13:32Z
dc.date.available2024-05-25T19:13:32Z
dc.descriptionNovel sulfate ester agents and the use of those agents for treating gastroesophageal reflux disease (GERD) are described, exemplary agents being of the formula [not included]: wherein Xis -OCH 2- or -CH 2 O-; Y is a group pendant from X comprising at least one -OSO 3 R 4 moiety, wherein R4 is H or a pharmaceutically acceptable cation; n is an integer from 1-3; and R 1 and R 2 are each independently selected from the group consisting of -H, a halogen with an atomic number from 9 to 53, -SO3 R4, -NCS, -NCO, -NH(CO)-OR 3 , -NH(CS)SR 3 , -NH(C=NH)OR 3 , -NHCOCH 2 Cl, -NHCOCH 2 Br, -NHCO-CH=CH 2 , -NHC(O)-CF 3 , wherein R 4 is H or a pharmaceutically acceptable cation.
dc.formatapplication/pdf
dc.identifierutoledo:1360
dc.identifieriid:utpatents-US6743820
dc.identifierPatent No.: US6743820
dc.identifierAppl. No.: 09/900336
dc.identifier.urihttps://hdl.handle.net/20.500.14324/6463
dc.language.isoeng
dc.publisherUnited States Patent and Trademark Office
dc.rightsNo Copyright - United States
dc.subject514/516
dc.subject558/11; 558/13
dc.subject558/14
dc.subject514/520
dc.titleMethods for protection of stratified squamous epithelium against injury by noxious substances and novel agents for use therefor
dc.typeText
dc.typepatent

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