Method of use of polymers containing cross-linked azo bonds for releasing therapeutic agents into the lower gastrointestinal tract

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United States Patent and Trademark Office

Abstract

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Polymers from ethylenically unsaturated monomers, cross-linked by a substituted or unsubstituted divinylazobenzene are useful as carriers or capsules for medicaments, which are degraded by the enzymes of the upper gastrointestinal tract or which must be transferred intact past the upper gastrointestinal tract, to deliver the medicament to the large intestine.Polymers containing monomeric units of the formula H2 C?CH--C6 H4 --N?N--M,wherein M is the residue of an amino-containing medicament, are useful as carriers for therapeutic agents or as therapeutic agents per se.

Keywords

424/487, 514/5.9, 514/9.7, 514/10.9, 514/54, 514/56, 514/150, 514/151, 514/568, 514/772, 514/778, 514/960, 514/961, 514/962, 514/963, 514/964, 534/573, 534/585, 534/588, 534/593, 534/599, 534/843, 534/887, 534/DIG.3

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