Vacuole-inducing compounds, methods of making and using the same

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Publisher

United States Patent and Trademark Office

Abstract

Description

Vacuole- or exosome-inducing indole-based chalcone and substituted triazole-hydrazone compounds that induce endosomal vacuolization and increase exosome yield, but do not trigger growth arrest or cell death, and methods of making and using are described.

Keywords

C12N5/00, A61K31/4439, A61K31/53, A61K31/5377, C12N1/38

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