Loading platform for three-dimensional tissue engineered scaffolds
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United States Patent and Trademark Office
Abstract
Description
A scaffold-stretching system includes at least one stretchable loading chamber configured to support a scaffold material and a supply of cells, such as human skin substitute cells, and is configured to allow for cultivation of a cellular three-dimensional scaffold; and a mechanical loading system is configured for application of cyclic and static uniaxial tensile mechanical loading on the cellular three-dimensional scaffold, and is configured to mimic the in vivo environment of musculoskeletal, cardiovascular, and other tissues that experience uniaxial strains.
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Keywords
C12M1/42, A61L27/24, A61L27/38, A61L27/54, A61L27/60, C12M1/12, C12M3/00, C12N5/00, C12Q1/6883, G01N33/50, C12N5/071