Protocol for preconcentration and quantification of microcystins using LC-MS

Methods for detecting and quantifying one or more microcystin compounds in a sample are described. The methods may include a preconcentration step, and generally utilize an LC-MS or LC-MS/MS analysis with an Orbitrap Fusion mass spectrometer or a QqQ mass spectrometer. The methods provide excellent recoveries and limits of quantification of microcystins.
Download pdf
Abstract/Description: Methods for detecting and quantifying one or more microcystin compounds in a sample are described. The methods may include a preconcentration step, and generally utilize an LC-MS or LC-MS/MS analysis with an Orbitrap Fusion mass spectrometer or a QqQ mass spectrometer. The methods provide excellent recoveries and limits of quantification of microcystins.
Subject(s): G01N33/68
G01N1/40
G01N33/569
Date Issued: 2020-10-20
Title: Protocol for preconcentration and quantification of microcystins using LC-MS.
Name(s): Isailovic, Dragan, inventor
Palagama, Dilrukshika, inventor
Baliu-Rodriguez, David, inventor
Levison, Bruce S., inventor
Kennedy, David J., inventor
Haller, Steven T., inventor
Hensley, Kenneth, inventor
The University of Toledo, assignee
Type of Resource: text
Genre: patent
Date Issued: 2020-10-20
Other Date: Date Filed: 2018-07-12
Publisher: United States Patent and Trademark Office
Physical Form: application/pdf
Extent: 88 p.
Abstract/Description: Methods for detecting and quantifying one or more microcystin compounds in a sample are described. The methods may include a preconcentration step, and generally utilize an LC-MS or LC-MS/MS analysis with an Orbitrap Fusion mass spectrometer or a QqQ mass spectrometer. The methods provide excellent recoveries and limits of quantification of microcystins.
Identifier(s): utpatents-US10809259 (IID)
Patent No.: US10809259 (patno)
Appl. No.: 16/033496 (appno)
Subject(s): G01N33/68
G01N1/40
G01N33/569
Held by: United States Patent and Trademark Office (USPTO) Public Search Facility
Location: University of Toledo Digital Repository
Rights Statement: No Copyright - United States
In Collections: