Injectable, biodegradable bone cements and methods of making and using same
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Abstract/Description: | Compositions of, methods of making, and methods of using alkaline earth phosphate bone cements are disclosed. A bone cement composition includes a powder comprising a basic source of calcium, magnesium, or strontium, a setting solution comprising H3PO4 and a buffer, and a biocompatible polymer that is incorporated into the setting solution. The powder is mixed with the setting solution to form a bone cement paste that either (a) sets into a hardened mass, or (b) is irradiated with electromagnetic radiation to form dry powders, the dry powders then being mixed with a second setting solution to form a radiation-assisted bone cement paste that sets into a hardened mass. |
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Subject(s): | C23C30/00 A61L24/00 A61B17/88 A61C5/62 A61K6/00 A61K6/06 A61K6/097 A61L24/02 A61L24/08 A61L27/32 |
Date Issued: | 2019-07-09 |
Title: | Injectable, biodegradable bone cements and methods of making and using same. |
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Name(s): |
Bhaduri, Sarit B, inventor Zhou, Huan, inventor Agarwal, Anand K., inventor Goel, Vijay K., inventor The University of Toledo, assignee |
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Type of Resource: | text | |
Genre: | patent | |
Date Issued: | 2019-07-09 | |
Other Date: | Date Filed: 2013-01-31 | |
Publisher: | United States Patent and Trademark Office | |
Physical Form: | application/pdf | |
Extent: | 25 p. | |
Abstract/Description: | Compositions of, methods of making, and methods of using alkaline earth phosphate bone cements are disclosed. A bone cement composition includes a powder comprising a basic source of calcium, magnesium, or strontium, a setting solution comprising H3PO4 and a buffer, and a biocompatible polymer that is incorporated into the setting solution. The powder is mixed with the setting solution to form a bone cement paste that either (a) sets into a hardened mass, or (b) is irradiated with electromagnetic radiation to form dry powders, the dry powders then being mixed with a second setting solution to form a radiation-assisted bone cement paste that sets into a hardened mass. | |
Identifier(s): |
utpatents-US10342893 (IID) Patent No.: US10342893 (patno) Appl. No.: 14/375927 (appno) |
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Subject(s): |
C23C30/00 A61L24/00 A61B17/88 A61C5/62 A61K6/00 A61K6/06 A61K6/097 A61L24/02 A61L24/08 A61L27/32 |
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Held by: | United States Patent and Trademark Office (USPTO) Public Search Facility | |
Location: | University of Toledo Digital Repository | |
Rights Statement: | No Copyright - United States | |
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