Inhibitors of ERCC1-XPF and methods of using the same
| Title: | Inhibitors of ERCC1-XPF and methods of using the same. |
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|---|---|---|
| Name(s): |
The University of Toledo, assignee Patrick, Stephan M., inventor Erhardt, Paul W., inventor Trabbic, Christopher J., inventor |
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| Type of Resource: | text | |
| Genre: | patent | |
| Publisher: | United States Patent and Trademark Office | |
| Other Date: | Date Filed: 2014-11-25 | |
| Date Issued: | 2017-11-21 | |
| Physical Form: | application/pdf | |
| Extent: | 15 p. | |
| Abstract/Description: | Compositions and methods for inhibiting the DNA repair protein complex, ERCC1-XPF, and methods to enhance clinical responses to anticancer drugs that interact with DNA such as cisplatin, and to overcome drug resistance due to DNA repair mechanisms, are described. | |
| Identifier(s): |
utpatents-US9821008 (IID) Patent No.: US9821008 (patno) Appl. No.: 15/038585 (appno) |
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| Subject(s): |
A61K33/24 A61K31/185 A61K31/255 A61K45/06 C07C309/47 C07C309/67 C07C309/73 C07C317/36 C07C323/66 |
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| Held by: | United States Patent and Trademark Office (USPTO) Public Search Facility | |
| Location: | University of Toledo Digital Repository | |
| Rights Statement: | No Copyright - United States | |
| In Collections: |