Analogs of peroxisome proliferator activated receptor (PPAR) agonists, and methods of using the same

Analogs of PPAR5 and analogs of 20-OH-PGE2, which are PPAR5 agonists and 20-OH-PGE2 antagonists, respectively, and methods of using the same for inducing osteogenesis or chondrogenesis, are disclosed.
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Abstract/Description: Analogs of PPAR5 and analogs of 20-OH-PGE2, which are PPAR5 agonists and 20-OH-PGE2 antagonists, respectively, and methods of using the same for inducing osteogenesis or chondrogenesis, are disclosed.
Subject(s): C07D277/22
A61K31/426
A61K31/5575
A61K45/06
Date Issued: 2017-07-04