Treatment of cancers with A-8R peptide
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Abstract/Description: | The present invention provides materials and methods useful to treat various sGCa1-expressing cancers. Materials include peptides which interfere with sGCa1's pro-survival functions, thereby resulting in apoptosis of sGCa1-expressing cells. In addition, the present invention provides screening assays, diagnostic assays, methods to prognose, methods to treat, and kits. |
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Subject(s): | A61K38/10 A61K31/7048 C07K7/06 C07K7/08 A61K38/08 A61K38/00 |
Date Issued: | 2016-03-29 |
Title: | Treatment of cancers with A-8R peptide. |
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Name(s): |
The University of Toledo, assignee Shemshedini, Lirim, inventor Chen, Shao-yong, inventor Cai, Changmeng, inventor Hsieh, Chen-Lin, inventor |
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Type of Resource: | text | |
Genre: | patent | |
Publisher: | United States Patent and Trademark Office | |
Other Date: | Date Filed: 2013-10-30 | |
Date Issued: | 2016-03-29 | |
Physical Form: | application/pdf | |
Extent: | 46 p. | |
Abstract/Description: | The present invention provides materials and methods useful to treat various sGCa1-expressing cancers. Materials include peptides which interfere with sGCa1's pro-survival functions, thereby resulting in apoptosis of sGCa1-expressing cells. In addition, the present invention provides screening assays, diagnostic assays, methods to prognose, methods to treat, and kits. | |
Identifier(s): |
utpatents-US9295686 (IID) Patent No.: US9295686 (patno) Appl. No.: 14/067116 (appno) |
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Subject(s): |
A61K38/10 A61K31/7048 C07K7/06 C07K7/08 A61K38/08 A61K38/00 |
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Held by: | United States Patent and Trademark Office (USPTO) Public Search Facility | |
Location: | University of Toledo Digital Repository | |
Rights Statement: | No Copyright - United States | |
In Collections: |