Materials and methods related to sodium/potassium adenosine triphosphase and cholesterol
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Abstract/Description: | This invention is based in part on the elucidation of new structural conformations and functions of the sodium/potassium adenosine triphosphate synthase (Na/K ATPase), and especially elucidation of new binding sites and interactions. The present invention provides practical applications of several surprising structural and functional relationships between Na/K ATPase and compounds which interact with Na/K ATPase. Disclosure of these structures and relationships provides insight and practical solutions to chemically affecting not only the Na/K ATPase interactions, but also regulators known to be upstream and downstream. |
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Subject(s): | 435/375 435/7.1 435/7.4 |
Date Issued: | 2014-09-16 |
Title: | Materials and methods related to sodium/potassium adenosine triphosphase and cholesterol. |
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Name(s): |
The University of Toledo, assignee Xie, Zi-jian, inventor Chen, Yiliang, inventor Wang, Haojie, inventor |
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Type of Resource: | text | |
Genre: | patent | |
Publisher: | United States Patent and Trademark Office | |
Other Date: | Date Filed: 2011-01-13 | |
Date Issued: | 2014-09-16 | |
Physical Form: | application/pdf | |
Extent: | 23 p. | |
Abstract/Description: | This invention is based in part on the elucidation of new structural conformations and functions of the sodium/potassium adenosine triphosphate synthase (Na/K ATPase), and especially elucidation of new binding sites and interactions. The present invention provides practical applications of several surprising structural and functional relationships between Na/K ATPase and compounds which interact with Na/K ATPase. Disclosure of these structures and relationships provides insight and practical solutions to chemically affecting not only the Na/K ATPase interactions, but also regulators known to be upstream and downstream. | |
Identifier(s): |
utpatents-US8835171 (IID) Patent No.: US8835171 (patno) Appl. No.: 13/521864 (appno) |
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Subject(s): |
435/375 435/7.1 435/7.4 |
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Held by: | United States Patent and Trademark Office (USPTO) Public Search Facility | |
Location: | University of Toledo Digital Repository | |
Rights Statement: | No Copyright - United States | |
In Collections: |