Treatment of Raynaud's phenomenon by inhibition of transient receptor potential melastatin-8 (TRPM-8)

Described herein are compositions for, and methods of treating, Raynaud's phenomenon. The compositions comprise a TRPM-8 antagonist formulated in a topical formulation in an amount effective to treat Raynaud's phenomenon.
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Abstract/Description: Described herein are compositions for, and methods of treating, Raynaud's phenomenon. The compositions comprise a TRPM-8 antagonist formulated in a topical formulation in an amount effective to treat Raynaud's phenomenon.
Subject(s): A61K9/00; A61K9/06; A61K31/4174; A61K31/55; A61K47/10; A61K47/14; A61K47/24; A61K47/38; A61P17/00
Date Issued: 2023-03-28