Altered peptide ligands of GAD65

Modified GAD65 compositions antagonize the activities of islet-specific T cells that contribute to the progression of one or more autoimmune disorders. The compositions are also antagonistic in humanized mice that express human HLA alleles associated with increased-risk of Type 1 diabetes.
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Abstract/Description: Modified GAD65 compositions antagonize the activities of islet-specific T cells that contribute to the progression of one or more autoimmune disorders. The compositions are also antagonistic in humanized mice that express human HLA alleles associated with increased-risk of Type 1 diabetes.
Subject(s): 530/328
424/185.1
Date Issued: 2011-08-09
Title: Altered peptide ligands of GAD65.
Name(s): The University of Toledo, assignee
Quinn, Anthony, inventor
Type of Resource: text
Genre: patent
Publisher: United States Patent and Trademark Office
Other Date: Date Filed: 2007-03-30
Date Issued: 2011-08-09
Physical Form: application/pdf
Extent: 14 p.
Abstract/Description: Modified GAD65 compositions antagonize the activities of islet-specific T cells that contribute to the progression of one or more autoimmune disorders. The compositions are also antagonistic in humanized mice that express human HLA alleles associated with increased-risk of Type 1 diabetes.
Identifier(s): utpatents-US7994279 (IID)
Patent No.: US7994279 (patno)
Appl. No.: 12/295793 (appno)
Subject(s): 530/328
424/185.1
Held by: United States Patent and Trademark Office (USPTO) Public Search Facility
Location: University of Toledo Digital Repository
Rights Statement: No Copyright - United States
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