utpatents-US6743820
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Abstract/Description: | Novel sulfate ester agents and the use of those agents for treating gastroesophageal reflux disease (GERD) are described, exemplary agents being of the formula: wherein X is -OCH2- or -CH2O-; Y is a group pendant from X comprising at least one -OSO3R4 moiety, wherein R4 is H or a pharmaceutically acceptable cation; n is an integer from 1-3; and R1 and R2 are each independently selected from the group consisting of -H, a halogen with an atomic number from 9 to 53, -SO3R4, -NCS, -NCO, -NH(CO)-OR3, -NH(CS)SR3, -NH(C=NH)OR3, -NHCOCH2Cl, -NHCOCH2Br, -NHCO-CH=CH2, -NHC(O)-CF3, wherein R4 is H or a pharmaceutically acceptable cation. |
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Subject(s): | 514/516 514/520 558/11 558/13 558/14 |
Date Issued: | 2004-06-01 |
Title: | Methods for protection of stratified squamous epithelium against injury by noxious substances and novel agents for use therefor. |
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Name(s): |
The University of Toledo, assignee Hudson, Richard A., inventor Tillekeratne, Viranga, inventor Tobey, Nelia A., inventor Orlando, Roy C., inventor |
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Type of Resource: | text | |
Genre: | patent | |
Publisher: | United States Patent and Trademark Office | |
Other Date: | Date Filed: 2001-07-05 | |
Date Issued: | 2004-06-01 | |
Physical Form: | application/pdf | |
Extent: | 32 p. | |
Abstract/Description: | Novel sulfate ester agents and the use of those agents for treating gastroesophageal reflux disease (GERD) are described, exemplary agents being of the formula: wherein X is -OCH2- or -CH2O-; Y is a group pendant from X comprising at least one -OSO3R4 moiety, wherein R4 is H or a pharmaceutically acceptable cation; n is an integer from 1-3; and R1 and R2 are each independently selected from the group consisting of -H, a halogen with an atomic number from 9 to 53, -SO3R4, -NCS, -NCO, -NH(CO)-OR3, -NH(CS)SR3, -NH(C=NH)OR3, -NHCOCH2Cl, -NHCOCH2Br, -NHCO-CH=CH2, -NHC(O)-CF3, wherein R4 is H or a pharmaceutically acceptable cation. | |
Identifier(s): |
utpatents-US6743820 (IID) Patent No.: US6743820 (patno) Appl. No.: 09/900336 (appno) |
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Subject(s): |
514/516 514/520 558/11 558/13 558/14 |
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Held by: | United States Patent and Trademark Office (USPTO) Public Search Facility | |
Location: | University of Toledo Digital Repository | |
Rights Statement: | No Copyright - United States | |
In Collections: |