Method for increasing HDL cholesterol levels using heteroaromatic phenylmethanes

An HDL cholesterol level inducing compound and a method of administering the compound having the structural formula I. ##STR1## wherein n is 1 or 2;R1 is a heteroaromatic substituent independently selected from a five-membered heteroaromatic ring having at least one N heteroatom, a six-membered heteroaromatic ring having at least one N heteroatom, or a fused ring system having at least one five-membered heteroaromatic ring having at least one N heteroatom;R2 is independently selected from --H or phenyl; andR3 is independently selected from --H, --CH3, --OH, phenyl, phenyl substituted with Cl, OCH3, CH3, or F, fused phenyl ring system, or six-membered heteroaromatic ring having at least one N heteroatom.
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Abstract/Description: An HDL cholesterol level inducing compound and a method of administering the compound having the structural formula I. ##STR1## wherein n is 1 or 2;R1 is a heteroaromatic substituent independently selected from a five-membered heteroaromatic ring having at least one N heteroatom, a six-membered heteroaromatic ring having at least one N heteroatom, or a fused ring system having at least one five-membered heteroaromatic ring having at least one N heteroatom;R2 is independently selected from --H or phenyl; andR3 is independently selected from --H, --CH3, --OH, phenyl, phenyl substituted with Cl, OCH3, CH3, or F, fused phenyl ring system, or six-membered heteroaromatic ring having at least one N heteroatom.
Subject(s): 514/277
514/399
514/400
514/427
544/333
546/272.7
546/343
548/340.1
548/346.1
Date Issued: 2000-08-15