Stable cell lines capable of expressing the adeno-associated virus replication gene
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Abstract/Description: | Stable packaging cell lines derived from human 293 cells which are transfected with an AAV vector having the AAV rep gene operably line to a heterologous transcription promoter, such as the metallothionein promoter, or an AAV Rep78 insensitive homologous promoter and which are capable of producing AAV Rep proteins and being useful for packaging recombinant AAV vectors containing target polynucleotides. |
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Subject(s): | 435/69.1 435/235.1 435/320.1 435/369 |
Date Issued: | 1998-11-17 |
Title: | Stable cell lines capable of expressing the adeno-associated virus replication gene. |
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Name(s): |
Medical College of Ohio, assignee Trempe, James P., inventor Yang, Qicheng, inventor |
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Type of Resource: | text | |
Genre: | patent | |
Publisher: | United States Patent and Trademark Office | |
Other Date: | Date Filed: 1995-01-09 | |
Date Issued: | 1998-11-17 | |
Physical Form: | application/pdf | |
Extent: | 17 p. | |
Abstract/Description: | Stable packaging cell lines derived from human 293 cells which are transfected with an AAV vector having the AAV rep gene operably line to a heterologous transcription promoter, such as the metallothionein promoter, or an AAV Rep78 insensitive homologous promoter and which are capable of producing AAV Rep proteins and being useful for packaging recombinant AAV vectors containing target polynucleotides. | |
Identifier(s): |
utpatents-US5837484 (IID) Patent No.: US5837484 (patno) Appl. No.: 08/362608 (appno) |
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Subject(s): |
435/69.1 435/235.1 435/320.1 435/369 |
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Held by: | United States Patent and Trademark Office (USPTO) Public Search Facility | |
Location: | University of Toledo Digital Repository | |
Rights Statement: | No Copyright - United States | |
In Collections: |