Histamine H3 -receptor antagonists and therapeutic uses thereof

The present invention provides novel compounds having activity as histamine H3 -receptor antagonists. The novel compounds include 4-imidazolyl-N-substituted pyrrolidines, piperidines, and cycloheptimides. The preferred compounds are 4-imidazolyl-N-(cycloalkyl/aryl-alkyl-carbonyl) piperidines such as 4-(1-cyclohexylvaleryol-4-piperidyl)-1H-imidazole.
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Abstract/Description: The present invention provides novel compounds having activity as histamine H3 -receptor antagonists. The novel compounds include 4-imidazolyl-N-substituted pyrrolidines, piperidines, and cycloheptimides. The preferred compounds are 4-imidazolyl-N-(cycloalkyl/aryl-alkyl-carbonyl) piperidines such as 4-(1-cyclohexylvaleryol-4-piperidyl)-1H-imidazole.
Subject(s): 546/210
546/203
548/314.7
Date Issued: 1997-05-27
Title: Histamine H3 -receptor antagonists and therapeutic uses thereof.
Name(s): The University of Toledo, assignee
Durant, Graham J., inventor
Khan, Amin M., inventor
Type of Resource: text
Genre: patent
Publisher: United States Patent and Trademark Office
Other Date: Date Filed: 1994-06-15
Date Issued: 1997-05-27
Physical Form: application/pdf
Extent: 21 p.
Abstract/Description: The present invention provides novel compounds having activity as histamine H3 -receptor antagonists. The novel compounds include 4-imidazolyl-N-substituted pyrrolidines, piperidines, and cycloheptimides. The preferred compounds are 4-imidazolyl-N-(cycloalkyl/aryl-alkyl-carbonyl) piperidines such as 4-(1-cyclohexylvaleryol-4-piperidyl)-1H-imidazole.
Identifier(s): utpatents-US5633382 (IID)
Patent No.: US5633382 (patno)
Appl. No.: 08/259926 (appno)
Subject(s): 546/210
546/203
548/314.7
Held by: United States Patent and Trademark Office (USPTO) Public Search Facility
Location: University of Toledo Digital Repository
Rights Statement: No Copyright - United States
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