Method of treating cancer tumors with imine porphyrin compounds
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Abstract/Description: | Purified imines of porphyrins, chlorins, bateriochlorins, chlorophylls, bacteriochlorophylls, purpurins, reduced purpurins, verdins, Diels Alder adducts, benzochlorins and metal complexes of the foregoing imines are disclosed. The formulas of the benzochlorinimines and of the benzochlorinimine metal complexes are set forth below: ##STR1## In specific examples, M in the metal complexes is a copper cation that is complexed with two of the nitrogens of the benzochlorinimine R' and R"" are methyl, and R1 through R8 are ethyl. |
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Subject(s): | 514/185 514/410 534/11 534/12 540/145 |
Date Issued: | 1996-04-30 |
Title: | Method of treating cancer tumors with imine porphyrin compounds. |
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Name(s): |
The University of Toledo; Medical College of Ohio, assignee Skalkos, Dimitris, inventor Selman, Steven H., inventor Hampton, James A., inventor |
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Type of Resource: | text | |
Genre: | patent | |
Publisher: | United States Patent and Trademark Office | |
Other Date: | Date Filed: 1995-01-19 | |
Date Issued: | 1996-04-30 | |
Physical Form: | application/pdf | |
Extent: | 56 p. | |
Abstract/Description: | Purified imines of porphyrins, chlorins, bateriochlorins, chlorophylls, bacteriochlorophylls, purpurins, reduced purpurins, verdins, Diels Alder adducts, benzochlorins and metal complexes of the foregoing imines are disclosed. The formulas of the benzochlorinimines and of the benzochlorinimine metal complexes are set forth below: ##STR1## In specific examples, M in the metal complexes is a copper cation that is complexed with two of the nitrogens of the benzochlorinimine R' and R"" are methyl, and R1 through R8 are ethyl. | |
Identifier(s): |
utpatents-US5512559 (IID) Patent No.: US5512559 (patno) Appl. No.: 08/375629 (appno) |
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Subject(s): |
514/185 514/410 534/11 534/12 540/145 |
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Held by: | United States Patent and Trademark Office (USPTO) Public Search Facility | |
Location: | University of Toledo Digital Repository | |
Rights Statement: | No Copyright - United States | |
In Collections: |