Methods for synthesizing glycinols, glyceollins I and II, compositions of selected intermediates, and therapeutic uses thereof
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Abstract/Description: | Two distinct methods are disclosed and claimed for synthesizing glyceollin I plus glyceollin II as a mixture and as their pure forms. Stereochemical isomers and various synthetic intermediates are also synthesized and claimed for their novel compositions of matter. All compounds and their mixtures are claimed for use in formulations that are useful to treat or prevent cancer, or that have utility as selective estrogen receptor modulators, such formulations including enhanced or medical foods, dietary supplements and ethical pharmaceutical agents. |
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Subject(s): | 514/453 |
Date Issued: | 2013-10-22 |
Title: | Methods for synthesizing glycinols, glyceollins I and II, compositions of selected intermediates, and therapeutic uses thereof. |
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Name(s): |
The United States of America, represented by the Secretary of Agriculture; Xavier University of Louisiana; The University of Toledo, assignee Erhardt, Paul W., inventor Khupse, Rahul S., inventor Sarver, Jefferey G., inventor Cleveland, Thomas E., inventor Boue, Stephen M., inventor Wiese, Thomas E., inventor Burow, Matthew E., inventor Mclachlan, John A., inventor |
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Type of Resource: | text | |
Genre: | patent | |
Publisher: | United States Patent and Trademark Office | |
Other Date: | Date Filed: 2009-03-03 | |
Date Issued: | 2013-10-22 | |
Physical Form: | application/pdf | |
Extent: | 35 p. | |
Abstract/Description: | Two distinct methods are disclosed and claimed for synthesizing glyceollin I plus glyceollin II as a mixture and as their pure forms. Stereochemical isomers and various synthetic intermediates are also synthesized and claimed for their novel compositions of matter. All compounds and their mixtures are claimed for use in formulations that are useful to treat or prevent cancer, or that have utility as selective estrogen receptor modulators, such formulations including enhanced or medical foods, dietary supplements and ethical pharmaceutical agents. | |
Identifier(s): |
utpatents-US8563599 (IID) Patent No.: US8563599 (patno) Appl. No.: 12/921013 (appno) |
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Subject(s): | 514/453 | |
Held by: | United States Patent and Trademark Office (USPTO) Public Search Facility | |
Location: | University of Toledo Digital Repository | |
Rights Statement: | No Copyright - United States | |
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