Materials and methods useful to induce cancer cell death via methuosis or autophagy or a combination thereof

Compounds, compositions, and methods useful for inducing cancer cell death via methuosis, autophagy, or a combination thereof, are described. The compounds have a 4-pyridyl group linked by a heterocyclic group to an aryl, heteroaryl, aralkyl, or heteroaryl alkyl.
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Abstract/Description: Compounds, compositions, and methods useful for inducing cancer cell death via methuosis, autophagy, or a combination thereof, are described. The compounds have a 4-pyridyl group linked by a heterocyclic group to an aryl, heteroaryl, aralkyl, or heteroaryl alkyl.
Subject(s): C07D513/04
A61K31/4439
A61K31/122
C07D401/14
Date Issued: 2022-08-09
Title: Materials and methods useful to induce cancer cell death via methuosis or autophagy or a combination thereof.
Name(s): Tiwari, Amit K., inventor
Karthikeyan, Chandrabose, inventor
Amawi, Haneen, inventor
Erhardt, Paul W., inventor
Trivedi, Piyush, inventor
The University of Toledo, assignee
Type of Resource: text
Genre: patent
Date Issued: 2022-08-09
Other Date: Date Filed: 2018-09-26
Publisher: United States Patent and Trademark Office
Physical Form: application/pdf
Extent: 72 p.
Abstract/Description: Compounds, compositions, and methods useful for inducing cancer cell death via methuosis, autophagy, or a combination thereof, are described. The compounds have a 4-pyridyl group linked by a heterocyclic group to an aryl, heteroaryl, aralkyl, or heteroaryl alkyl.
Identifier(s): utpatents-US11406626 (IID)
Patent No.: US11406626 (patno)
Appl. No.: 16/650986 (appno)
Subject(s): C07D513/04
A61K31/4439
A61K31/122
C07D401/14
Held by: United States Patent and Trademark Office (USPTO) Public Search Facility
Location: University of Toledo Digital Repository
Rights Statement: No Copyright - United States
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