Materials and methods useful to induce cancer cell death via methuosis or autophagy or a combination thereof

Compounds, compositions, and methods useful for inducing cancer cell death via methuosis, autophagy, or a combination thereof, are described. The compounds have a 4-pyridyl group linked by a heterocyclic group to an aryl, heteroaryl, aralkyl, or heteroaryl alkyl.
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Abstract/Description: Compounds, compositions, and methods useful for inducing cancer cell death via methuosis, autophagy, or a combination thereof, are described. The compounds have a 4-pyridyl group linked by a heterocyclic group to an aryl, heteroaryl, aralkyl, or heteroaryl alkyl.
Subject(s): C07D513/04
A61K31/4439
A61K31/122
C07D401/14
Date Issued: 2022-08-09