Imidazole-based anticancer agents and derivatives thereof, and methods of making and using same

midazole-based anticancer agents and derivatives thereof, as well as methods of making and methods of using the same, are described. The imidazole-based anticancer agents are HDAC inhibitor compounds having a 1-(1H-imidazol-2-yl)ethan-1-one or 1-(1H-imidazol-2-yl)ethane-1-thione moiety.
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Abstract/Description: midazole-based anticancer agents and derivatives thereof, as well as methods of making and methods of using the same, are described. The imidazole-based anticancer agents are HDAC inhibitor compounds having a 1-(1H-imidazol-2-yl)ethan-1-one or 1-(1H-imidazol-2-yl)ethane-1-thione moiety.
Subject(s):
C07D417/12
C07D233/64
Date Issued: 2021-08-24
Title: Imidazole-based anticancer agents and derivatives thereof, and methods of making and using same.
Name(s): Tillekeratne, Viranga, inventor
Al-Hamashi, Ayad, inventor
Dlamini, Samkeliso, inventor
Alqahtani, Abdulateef Saeed S., inventor
Karaj, Endri, inventor
The University of Toledo, assignee
Type of Resource: text
Genre: patent
Date Issued: 2021-08-24
Other Date: Date Filed: 2018-08-17
Publisher: United States Patent and Trademark Office
Physical Form: application/pdf
Extent: 37 p.
Abstract/Description: midazole-based anticancer agents and derivatives thereof, as well as methods of making and methods of using the same, are described. The imidazole-based anticancer agents are HDAC inhibitor compounds having a 1-(1H-imidazol-2-yl)ethan-1-one or 1-(1H-imidazol-2-yl)ethane-1-thione moiety.
Identifier(s): utpatents-US11098038 (IID)
Patent No.: US11098038 (patno)
Appl. No.: 16/638587 (appno)
Subject(s):
C07D417/12
C07D233/64
Held by: United States Patent and Trademark Office (USPTO) Public Search Facility
Location: University of Toledo Digital Repository
Rights Statement: No Copyright - United States
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