Biosensor device to target analytes in situ, in vivo, and/or in real time, and methods of making and using the same
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Abstract/Description: | A biosensor device for the real-time detection of a target analyte includes a receptor component operatively connected to a transducer component which is adapted to interpret and transmit a detectable signal. The receptor component includes a sensing element capable of detecting and binding to at least one target analyte, and a self-assembled monolayer (SAM) layer. The SAM layer is positioned between and in contact with the sensing element and an electrode such that the sensing element, in the presence of the target analyte, causes a detectable signal capable of being transmitted to the electrode. The transducer component includes the electrode and microprocessor configured to screen noise and to pick up impedance change at a very low frequency range. |
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Subject(s): | G01N27/327 A61B5/1473 G01N33/543 G01N33/569 A61B5/145 A61B5/00 |
Date Issued: | 2020-12-01 |
Title: | Biosensor device to target analytes in situ, in vivo, and/or in real time, and methods of making and using the same. |
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Name(s): |
Agarwal, Anand K., inventor Goel, Vijay K., inventor Kim, Dong-shik, inventor Yoon, Do Young, inventor Lin, Boren, inventor Feyzizarnagh, Hamid, inventor The University of Toledo, assignee |
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Type of Resource: | text | |
Genre: | patent | |
Date Issued: | 2020-12-01 | |
Other Date: | Date Filed: 2014-03-011 | |
Publisher: | United States Patent and Trademark Office | |
Physical Form: | application/pdf | |
Extent: | 25 p. | |
Abstract/Description: | A biosensor device for the real-time detection of a target analyte includes a receptor component operatively connected to a transducer component which is adapted to interpret and transmit a detectable signal. The receptor component includes a sensing element capable of detecting and binding to at least one target analyte, and a self-assembled monolayer (SAM) layer. The SAM layer is positioned between and in contact with the sensing element and an electrode such that the sensing element, in the presence of the target analyte, causes a detectable signal capable of being transmitted to the electrode. The transducer component includes the electrode and microprocessor configured to screen noise and to pick up impedance change at a very low frequency range. | |
Identifier(s): |
utpatents-US10849540 (IID) Patent No.: US10849540 (patno) Appl. No.: 14/774499 (appno) |
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Subject(s): |
G01N27/327 A61B5/1473 G01N33/543 G01N33/569 A61B5/145 A61B5/00 |
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Held by: | United States Patent and Trademark Office (USPTO) Public Search Facility | |
Location: | University of Toledo Digital Repository | |
Rights Statement: | No Copyright - United States | |
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