Potent phthalate inhibitors of aspartate N-acetyltransferase and selective aspartate pathway inhibitors

Phthalate derivatives that are aspartate-P-semialdehyde dehydrogenase (ASADH) inhibitor compounds, aspartate N-acetyltransferase (ANAT) inhibitor compounds, or both, are described, as well as methods of making the same, and methods of using the same.
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Abstract/Description: Phthalate derivatives that are aspartate-P-semialdehyde dehydrogenase (ASADH) inhibitor compounds, aspartate N-acetyltransferase (ANAT) inhibitor compounds, or both, are described, as well as methods of making the same, and methods of using the same.
Subject(s): C07C227/18
A61K31/198
C07C229/38
A61P25/28
A61P31/00
Date Issued: 2019-10-22