Method for modifying surfaces for better osseointegration

In one aspect, there is provided a method for preparing a biocompatible coated substrate. The method generally includes: depositing nucleation amorphous calcium phosphate sites on at least a portion of an outer surface of a substrate by: exposing at least the portion of the outer surface to a mixture having a favorable Ca/P molar ratio, and irradiating with microwave energy; and, stabilizing the deposited nucleation amorphous calcium phosphate sites on the portion of the outer surface. In another aspect, there is provided herein a method for preparing a biocompatible coated substrate.
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Abstract/Description: In one aspect, there is provided a method for preparing a biocompatible coated substrate. The method generally includes: depositing nucleation amorphous calcium phosphate sites on at least a portion of an outer surface of a substrate by: exposing at least the portion of the outer surface to a mixture having a favorable Ca/P molar ratio, and irradiating with microwave energy; and, stabilizing the deposited nucleation amorphous calcium phosphate sites on the portion of the outer surface. In another aspect, there is provided herein a method for preparing a biocompatible coated substrate.
Subject(s): A61L31/08
A61L27/32
A61L27/00
A61L27/12
A61L27/54
A61L29/10
Date Issued: 2019-08-06
Title: Method for modifying surfaces for better osseointegration.
Name(s): Bhaduri, Sarit B., inventor
Goel, Vijay K., inventor
Zhou, Huan, inventor
The University of Toledo, assignee
Type of Resource: text
Genre: patent
Date Issued: 2019-08-06
Other Date: Date Filed: 2012-10-31
Publisher: United States Patent and Trademark Office
Physical Form: application/pdf
Extent: 17 p.
Abstract/Description: In one aspect, there is provided a method for preparing a biocompatible coated substrate. The method generally includes: depositing nucleation amorphous calcium phosphate sites on at least a portion of an outer surface of a substrate by: exposing at least the portion of the outer surface to a mixture having a favorable Ca/P molar ratio, and irradiating with microwave energy; and, stabilizing the deposited nucleation amorphous calcium phosphate sites on the portion of the outer surface. In another aspect, there is provided herein a method for preparing a biocompatible coated substrate.
Identifier(s): utpatents-US10369253 (IID)
Patent No.: US10369253 (patno)
Appl. No.: 14/355051 (appno)
Subject(s): A61L31/08
A61L27/32
A61L27/00
A61L27/12
A61L27/54
A61L29/10
Held by: United States Patent and Trademark Office (USPTO) Public Search Facility
Location: University of Toledo Digital Repository
Rights Statement: No Copyright - United States
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