Conformationally restrained epothilone analogues as anti-leukemic agents
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Abstract/Description: | A method for synthesizing anti-leukemic epothilone analogues includes rigidifying a region between the macrolactone ring and the aromatic side-chain. The anti-leukemic compositions are non-naturally occurring epothilone analogue that are rigidified between the macrolactone ring and the aromatic side-chain. |
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Subject(s): | 514/228.2 514/323 540/602 544/373 546/147 546/200 548/517 |
Date Issued: | 2013-05-07 |
Title: | Conformationally restrained epothilone analogues as anti-leukemic agents. |
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Name(s): |
The University of Toledo, assignee Tillekeratne, Viranga, inventor Hudson, Richard A., inventor Alhamadsheh, Mamoun, inventor |
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Type of Resource: | text | |
Genre: | patent | |
Publisher: | United States Patent and Trademark Office | |
Other Date: | Date Filed: 2008-03-20 | |
Date Issued: | 2013-05-07 | |
Physical Form: | application/pdf | |
Extent: | 32 p. | |
Abstract/Description: | A method for synthesizing anti-leukemic epothilone analogues includes rigidifying a region between the macrolactone ring and the aromatic side-chain. The anti-leukemic compositions are non-naturally occurring epothilone analogue that are rigidified between the macrolactone ring and the aromatic side-chain. | |
Identifier(s): |
utpatents-US8435983 (IID) Patent No.: US8435983 (patno) Appl. No.: 12/532829 (appno) |
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Subject(s): |
514/228.2 514/323 540/602 544/373 546/147 546/200 548/517 |
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Held by: | United States Patent and Trademark Office (USPTO) Public Search Facility | |
Location: | University of Toledo Digital Repository | |
Rights Statement: | No Copyright - United States | |
In Collections: |