Muscarinic receptor agonists

A compound of Formula (I): ##STR1## wherein R is a linkage independently selected from (CH2)12 or (CH2)4 O3 ; and acid addition salts, solvates and hydrates thereof. The compounds have unusually high affinity for muscarinic receptors, and exhibit agonist activity useful in the treatment of neurological and other disorders, in which stimulating cholinergic activity is desirable.
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Abstract/Description: A compound of Formula (I): ##STR1## wherein R is a linkage independently selected from (CH2)12 or (CH2)4 O3 ; and acid addition salts, solvates and hydrates thereof. The compounds have unusually high affinity for muscarinic receptors, and exhibit agonist activity useful in the treatment of neurological and other disorders, in which stimulating cholinergic activity is desirable.
Subject(s): 514/333
546/256
Date Issued: 2000-08-01
Title: Muscarinic receptor agonists.
Name(s): The University of Toledo, assignee
Rajeswaran, Walajapet G., inventor
Messer, William S., inventor
Type of Resource: text
Genre: patent
Publisher: United States Patent and Trademark Office
Other Date: Date Filed: 1999-01-22
Date Issued: 2000-08-01
Physical Form: application/pdf
Extent: 5 p.
Abstract/Description: A compound of Formula (I): ##STR1## wherein R is a linkage independently selected from (CH2)12 or (CH2)4 O3 ; and acid addition salts, solvates and hydrates thereof. The compounds have unusually high affinity for muscarinic receptors, and exhibit agonist activity useful in the treatment of neurological and other disorders, in which stimulating cholinergic activity is desirable.
Identifier(s): utpatents-US6096767 (IID)
Patent No.: US6096767 (patno)
Appl. No.: 09/236030 (appno)
Subject(s): 514/333
546/256
Held by: United States Patent and Trademark Office (USPTO) Public Search Facility
Location: University of Toledo Digital Repository
Rights Statement: No Copyright - United States
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