IL-12 Stimulation of Neonatal immunity
| Title: | IL-12 Stimulation of Neonatal immunity. |
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|---|---|---|
| Name(s): |
Medical College of Ohio, assignee Metzger, Dennis W., inventor Arulanandam, Bernard P., inventor |
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| Type of Resource: | text | |
| Genre: | patent | |
| Publisher: | United States Patent and Trademark Office | |
| Other Date: | Date Filed: 1998-03-05 | |
| Date Issued: | 1999-11-16 | |
| Physical Form: | application/pdf | |
| Extent: | 18 p. | |
| Abstract/Description: | The present invention relates to a method of inducing a Th1-like response against a pathogen in a neonatal host, which comprises administering to the neonatal host an effective amount of IL-12 and an antigen of the pathogen. Also encompassed by the present invention is a method of overcoming suppression of interferon-? (IFN-?) expression in a neonatal host due to exposure of the neonatal host to a pathogen or an antigen, which comprises administering to the neonatal host an effective amount of IL-12 and the antigen. The present invention also relates to a method of enhancing the cytokine expression against or in response to a pathogen in a neonatal host, which comprises administering to the neonatal host an effective amount of IL-12 and an antigen of the pathogen. | |
| Identifier(s): |
utpatents-US5985264 (IID) Patent No.: US5985264 (patno) Appl. No.: 09/035593 (appno) |
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| Subject(s): |
424/85.2 424/85.4 424/184.1 424/191.1 424/204.1 424/234.1 424/264.1 424/269.1 530/350 |
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| Held by: | United States Patent and Trademark Office (USPTO) Public Search Facility | |
| Location: | University of Toledo Digital Repository | |
| Rights Statement: | No Copyright - United States | |
| In Collections: |