Document Type

Patent

Abstract

A method for synthesizing anti-leukemic epothilone analogues includes rigidifying a region between the macrolactone ring and the aromatic side-chain. The anti-leukemic compositions are non-naturally occurring epothilone analogue that are rigidified between the macrolactone ring and the aromatic side-chain.

Patent Country

US

Patent Number

US8435983

Publication Date

5-7-2013

Assignee(s)

The University of Toledo

Application Number

12/532829

Filing Date

March 2008

Primary Class

514/228.2

Secondary Class

514/323; 540/602; 544/373; 546/147; 546/200; 548/517

Rights

These materials are free of copyright restrictions and are in the public domain within the United States only. The USPTO reserves the right to assert copyright protection internationally.

Institution

The University of Toledo

Repository

University of Toledo Libraries

Digital Publisher

Digital Initiatives

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