Document Type

Patent

Abstract

The present invention provides materials and methods useful to treat various sGCα1-expressing cancers. Materials include peptides which interfere with sGCα1's pro-survival functions, thereby resulting in apoptosis of sGCα1-expressing cells. In addition, the present invention provides screening assays, diagnostic assays, methods to prognose, methods to treat, and kits.

Patent Country

United States

Patent Number

US9393254

Publication Date

7-19-2016

Assignee(s)

The University of Toledo

Application Number

14/067084

Filing Date

10-30-2013

Primary Class

A61K38/10; A61K31/7048; A61K38/08; C07K7/06; C07K7/08;

Secondary Class

A61K38/00

Rights

These materials are free of copyright restrictions and are in the public domain within the United States only. The USPTO reserves the right to assert copyright protection internationally.

Institution

The University of Toledo

Repository

University of Toledo Digital Libraries

Digital Publisher

Digital Initiatives

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