Document Type
Patent
Abstract
New piperidinyl-alkyl-benzamides and salts thereof are disclosed, together with a method for the production of the benzamides and salts. The benzamides, which have beta-adrenergic agonist effects, have the general formula ##STR1## The hydrochlorides which exemplify the salts, have the general formula ##STR2## In the foregoing formulas R is hydrogen, an alkyl group having from 1 to 4 carbon atoms, an alkoxy group having from 1 to 4 carbon atoms, halo, amino, hydroxy or trifluoromethyl, n is 1, 2 or 3 when R is methoxy but is otherwise 1, and x is 1, 2 or 3. The hydrochloride salts of the benzamides according to the invention can be produced by the reactions illustrated below: ##STR3## Wherein R, n and x have the meanings set forth above and Y can be --Cl, --F, or --OCH3.
Patent Country
US
Patent Number
US4035373
Publication Date
7-12-1977
Assignee(s)
The University of Toledo
Application Number
05/660652
Filing Date
February 1976
Primary Class
546/233
Secondary Class
514/935
Rights
These materials are free of copyright restrictions and are in the public domain within the United States only. The USPTO reserves the right to assert copyright protection internationally.
Institution
The University of Toledo
Repository
University of Toledo Libraries
Digital Publisher
Digital Initiatives
Recommended Citation
Roll, William D., "Preparation of piperidinyl-alkyl-benzamides" (1977). University of Toledo U.S. Patents. 239.
http://utdr.utoledo.edu/utpatents/239