Abstract

Substituted 1,4,5,6 -tetrahydropyrimidine compositions, substituted 1,2,3,6 -tetrahydropyrimidine compositions and substituted 3,4,5,6 -tetrahydropyridine compositions are disclosed. They are useful for stimulating muscarinic receptors including, for example, treating the symptoms of cognitive disorders, especially impaired memory, which are associated with decreased acetylcholine synthesis and cholinergic cell degeneration.

Document Type

Patent

Primary Class

514/275

Secondary Class

514/256; 514/269; 514/272; 514/336; 514/340; 514/342; 514/349; 514/352; 514/354; 514/356; 514/357; 544/298; 544/331; 544/332; 544/333; 544/335; 544/354; 544/356; 544/357; 546/268.7; 546/269.4; 546/281.4; 546/283.7; 546/290; 546/297; 546/304; 546/309; 546/310; 546/311; 546/312

Application Number

08/224271

Filing Date

April 1994

Patent Number

US5403845

Assignee(s)

The University of Toledo

Publication Date

4-4-1995

Patent Country

US

Language

en_US

Institution

The University of Toledo

Repository

University of Toledo Libraries

Digital Publisher

Digital Initiatives

Rights

These materials are free of copyright restrictions and are in the public domain within the United States only. The USPTO reserves the right to assert copyright protection internationally.

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Rights Statement

Rights Statement

No Copyright - United States. URI: http://rightsstatements.org/vocab/NoC-US/1.0/
The organization that has made the Item available believes that the Item is in the Public Domain under the laws of the United States, but a determination was not made as to its copyright status under the copyright laws of other countries. The Item may not be in the Public Domain under the laws of other countries. Please refer to the organization that has made the Item available for more information.