Purified imines of porphyrins, chlorins, bateriochlorins, chlorophylls, bacteriochlorophylls, purpurins, reduced purpurins, verdins, Diels Alder adducts, benzochlorins and metal complexes of the foregoing imines are disclosed for retarding growth of cancer tumors such as bladder tumors. The formulas of the benzochlorinimines and of the benzochlorinimine metal complexes are set forth below: ##STR1## In specific examples, M in the metal complexes is a copper cation that is complexed with two of the nitrogens of the benzochlorinimine R' and R"" are methyl, and R1 through R8 are ethyl.
The University of Toledo; Medical College of Ohio
534/11; 534/12; 540/145
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The University of Toledo
University of Toledo Libraries
Skalkos, Dimitris; Selman, Steven H.; and Hampton, James A., "Production and use of imines of porphyrins, of porphyrin derivatives and of related compounds, and of compositions containing such imines" (1995). University of Toledo U.S. Patents. 181.