Document Type

Patent

Abstract

Stable packaging cell lines derived from human 293 cells which are transfected with an AAV vector having the AAV rep gene operably line to a heterologous transcription promoter, such as the metallothionein promoter, or an AAV Rep78 insensitive homologous promoter and which are capable of producing AAV Rep proteins and being useful for packaging recombinant AAV vectors containing target polynucleotides.

Patent Country

US

Patent Number

US5837484

Publication Date

11-17-1998

Assignee(s)

Medical College of Ohio

Application Number

08/362608

Filing Date

January 1995

Primary Class

435/69.1

Secondary Class

435/235.1; 435/320.1; 435/369

Rights

These materials are free of copyright restrictions and are in the public domain within the United States only. The USPTO reserves the right to assert copyright protection internationally.

Institution

The University of Toledo

Repository

University of Toledo Libraries

Digital Publisher

Digital Initiatives

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