Document Type

Patent

Abstract

A compound of Formula (I): ##STR1## wherein R is independently selected from (CH2)9-12, (CH2 CH2)2 O, (CH2 CH2)3 O2, (CH2 CH2)4 O3, (CH2 CH2)5 O4, (CH2 CH2)6 O5 or (CH2 CH2 CH2)3 O2 ; or an acid addition salt or hydrate thereof. The compounds, with improved water solubility, have unusually high affinity for muscarinic receptors, and exhibit agonist activity useful in the treatment of neurological and other disorders, in which stimulating cholinergic activity is desirable.

Patent Country

US

Patent Number

US6211204

Publication Date

4-3-2001

Assignee(s)

The University of Toledo

Application Number

09/483334

Filing Date

January 2000

Primary Class

514/342

Secondary Class

546/187; 546/268.7

Rights

These materials are free of copyright restrictions and are in the public domain within the United States only. The USPTO reserves the right to assert copyright protection internationally.

Institution

The University of Toledo

Repository

University of Toledo Libraries

Digital Publisher

Digital Initiatives

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