A compound of formula (I): ##STR1## wherein, R1 is independently selected from methyl and ethyl and R2 is independently selected from hydrogen, alkyl, and substituted alkyl. The compound is capable of functioning as a ligand and complexing with paramagnetic Fe(III) ion for use as a second-sphere contrast enhancing agent for magnetic resonance imaging of tissue. The present invention also relates to a method of administering the second sphere contrast agent.
The University of Toledo; Schering Aktiengesellschaft
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The University of Toledo
University of Toledo Libraries
Davies, Julian A.; Ebert, Wolfgang; Raduechel, Bernd; and Schmitt-Willich, Heribert, "Iron(III) complexes as contrast agents for image enhancement in magnetic resonance imaging" (2001). University of Toledo U.S. Patents. 118.