Document Type

Patent

Abstract

The present invention provides materials and methods to induce cell death by methuosis, a non-apoptotic cell death mechanism, to induce vacuolization without cell death, or to induce cell death without vacuolization. Small molecules herein are useful for treating cell proliferation disorders or anomalies, particularly, but not exclusively, cancer. Methods related to the research and pharmaceutical use of the small molecules are also provided herein.

Patent Country

US

Patent Number

US9023871

Publication Date

5-5-2015

Assignee(s)

The University of Toledo

Application Number

14/246558

Filing Date

April 2014

Primary Class

514/339

Secondary Class

435/366; 435/375; 514/419; 546/277.4; 546/278.1; 548/493

Rights

These materials are free of copyright restrictions and are in the public domain within the United States only. The USPTO reserves the right to assert copyright protection internationally.

Institution

The University of Toledo

Repository

University of Toledo Libraries

Digital Publisher

Digital Initiatives

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