Document Type

Patent

Abstract

A method for removing acyl-groups appended by an ester linkage to the 2′-hydroxyl group present in paclitaxel-related molecules comprising treatment with alcohol under non-acidic conditions. 2′,7-bis-Monochloroacetylpaclitaxel analogs are converted to their corresponding 7-monochloroacetyl derivatives by treatment with alcohol under non-acidic conditions

Patent Country

US

Patent Number

US6846937

Publication Date

1-25-2005

Assignee(s)

The University of Toledo

Application Number

10/491576

Filing Date

September 2002

Primary Class

549/510

Secondary Class

549/511

Rights

These materials are free of copyright restrictions and are in the public domain within the United States only. The USPTO reserves the right to assert copyright protection internationally.

Institution

The University of Toledo

Repository

University of Toledo Libraries

Digital Publisher

Digital Initiatives

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