Asians represent the fastest growing ethnic group in the United States. Despite significant diversity within the group, many transplant studies treat Asians as a homogeneous entity. We compared patient and graft survival among major Asian ethnicities to determine whether any subgroup has superior outcomes.
Materials and Methods
We conducted a retrospective analysis of kidney transplants on Asian patients between 2001 and 2012. Covariates included gender, age, comorbidities, and donor category. Primary outcomes included one-year patient and graft survival. Secondary outcomes included delayed graft function (DGF) and rejection as cause of graft loss and death.
91 Asian patients were identified. Due to the large proportion of Chinese patients (n=37), we grouped other Asians into one entity (n=54) for statistical comparison among Chinese, other Asians, and Whites (n=346). Chinese subjects had significantly lower body mass index (BMI) (p=0.001) and had the lowest proportion of living donors (p
Our study confirms outcomes differences among Asian subgroups in kidney transplantation. Chinese demonstrate better patient survival at one year than Whites and non-Chinese Asians despite fewer live donors. Lower BMI scores may partly explain this. Larger, long-term studies are needed to elucidate outcome disparities among Asian subgroups.
The University of Toledo
Ward M. Canaday Center for Special Collections
Translation: The University of Toledo Journal of Medical Sciences
Karipineni, Farah; Parsikia, Afshin; Chang, PoNan; Pang, John; Campos, Stalin; Khanmoradi, Kamran; Zaki, Radi; and Ortiz, Jorge
"Dispelling the myth of Asian homogeneity: Improved outcomes of Chinese Americans after kidney transplantation,"
Translation: The University of Toledo Journal of Medical Sciences: Vol. 3
, Article 2.
Available at: http://utdr.utoledo.edu/translation/vol3/iss1/2